Cancer Research UK is abandoning its Race for Life event at Ardingly.
The charity says it is reducing the number of smaller Race for Life events across the UK, which includes Ardingly.
Suzi Dent, event manager for the Sussex, said: “Race for Life raises money to fund life-saving research. So we owe it to our participants and supporters to ensure that we raise as much money as possible in the most cost-efficient way.
“Although 1,289 women took part at our Ardingly event in June, entries were lower than anticipated. Taking the costs of staging the event into consideration, we have had to take the difficult decision not to run it again in 2013.”
She added: “We want to express our heart-felt thanks to everyone who has taken part in Race for Life in Ardingly and we hope our supporters will understand the reason for this difficult decision for 2013.”
Ardingly and the South of England Showground where the event was held, have lost out to Horsham where a new Race for Life event is being created.
Cancer Research UK said there was a bigger population to draw on around Horsham than Ardingly, while the numbers at Ardingly, which had started at nearer 2,000 when the first race was held, were well below target this year.
A spokesman said: “It would be wonderful if each event filled every year but, sadly, they don’t so we have to keep trying new locations, venues and times.
“It won’t be as convenient for those who had Ardingly on their doorstep but there are other events all over Sussex – Hastings, Eastbourne, Brighton, Worthing, Crawley and now Horsham – so we hope that those who did Ardingly will continue to support us and transfer there.”
A Race for Life will now be held in Horsham Park on June 2 with the Crawley venue staging its event on June 19.